Va Office Of Research And Development

This study tested a special grape seed extract (leucoselect phytosome) given before surgery to people with early-stage lung cancer. The goal was to see if it was safe and could slow tumor growth. Only 6 people took part, and the study was stopped early, so we don't have clear ans…

This study tested whether two specific antibiotics—fidaxomicin and a special vancomycin regimen—work better than standard vancomycin for people with repeat Clostridium difficile infections. The goal was to see which treatment best stops symptoms and prevents the infection from co…

This study aimed to see if adding Problem Solving Therapy to standard suicide safety planning could reduce suicidal thoughts in older veterans (age 55+) with depression, anxiety, or PTSD. The trial planned to enroll 117 veterans but was terminated early. The approach focused on t…

This study tested whether a brief 4-session version of cognitive-behavioral therapy (CBT) works as well as the standard 6-session version for treating insomnia in veterans. Insomnia is very common among veterans and can harm daily life and health. The study enrolled 15 veterans w…

This study aimed to understand why erythropoietin (EPO), a drug used to treat anemia, can raise blood pressure in people with chronic kidney disease. Researchers planned to compare blood pressure changes in patients who started EPO immediately versus those who delayed treatment. …

This study tested whether short, repeated bursts of low oxygen (like mild breath-holding) paired with hand exercises could help people with chronic spinal cord injury regain grip and pinch strength. The trial was stopped early and included only 50 participants, so results are lim…

This study aimed to see if a quick brain wave test could predict which veterans with PTSD or depression would respond well to common antidepressant medications (SSRIs). Researchers planned to enroll 94 participants, but the study was stopped early after only 26 people took part. …

This study looked at how the brain controls hand movements after a spinal cord injury. Researchers tested whether non-invasive brain stimulation and startle techniques, combined with motor training, could improve grasping. The study included both healthy people and those with chr…

This study looked at whether oxytocin, a natural brain chemical that helps with social bonding, could improve social functioning in veterans with schizophrenia. Researchers planned to give oxytocin and use brain scans to see who might benefit most. The study was stopped early, so…

This small pilot study tested whether a home-based conservative care plan is practical and acceptable for people with advanced chronic kidney disease who decide not to start dialysis. Only 2 patients enrolled, and researchers interviewed them, their caregivers, and doctors to und…

This study tested a smartphone-based program to help veterans with serious mental illness (like PTSD, bipolar disorder, or schizophrenia) better recognize and describe their emotions. The goal was to see if improving emotion awareness could lower suicide risk. Only 11 veterans to…