Uppsala University

This early-stage study tested a single dose of mesenchymal stromal cells in 7 COVID-19 patients with severe acute respiratory distress syndrome (ARDS) who were on ventilators. The main goal was to check safety, looking for serious side effects like heart problems or blood clots w…

This study compared two common diabetes drugs—dapagliflozin and metformin—in over 2,000 people with early type 2 diabetes (diagnosed less than 4 years). The goal was to see which drug better prevents serious complications like death, heart attack, stroke, heart failure, kidney di…

This study tested whether a special type of hip implant (dual mobility cup) can prevent the hip from popping out of place after a total hip replacement for a broken hip. The trial involved 1,600 elderly patients with a specific type of hip fracture. Researchers compared the dual …

This study tested a 'no-touch' method for taking veins from the leg during heart bypass surgery, compared to the usual technique. Over 900 patients were followed for two years to see if the no-touch method kept the vein grafts open better. The goal is to improve long-term success…

This study tested a new online treatment program for people exhausted from long-term stress. 26 participants used a digital therapy that combines education, coping skills, and support. The goal was to see if the program could reduce symptoms of exhaustion and improve well-being.

This study tested whether trained dogs can help children who miss a lot of school. 64 students in grades 3-9 with at least 15% absence were randomly assigned to receive either dog-assisted support or standard teaching for 30 minutes twice a week for 10-12 weeks. The goal was to s…

This study looked at two ways to assess ADHD in children aged 8-17: a brief protocol (medical history, interview, rating scales) and a comprehensive one that also includes neuropsychological testing. Researchers wanted to see if the shorter method is as reliable, valid, and cost-…

This study looked at over 315,000 very old patients (80+) admitted to Swedish ICUs. It found that the longer a patient stayed in a regular hospital ward before being moved to the ICU, the higher their risk of dying within 30 days. The research highlights the need for careful deci…

This completed study looked at 4000 COVID-19 patients in Swedish ICUs who needed a breathing machine. Researchers compared outcomes based on how soon after starting ventilation a tracheostomy was performed. The goal was to see if earlier or later timing affects how many days pati…

This study tested a new wearable capnograph called MARIE in an ambulance setting. The device measures exhaled carbon dioxide and breathing rate. 20 healthy volunteers and 30 patients being transported by ambulance participated. The goal was to see if the device gives reliable rea…

This study looks at how a cardiac arrest affects brain function, including memory, thinking, and emotions. Researchers will follow 48 survivors for one year, using cognitive tests and brain scans (fMRI) to track changes. Their results will be compared to a healthy control group t…

This study looked at 1,003 people who had a cardiac arrest outside the hospital and were revived. It compared getting a coronary angiogram (an X-ray of the heart's arteries) within 2 hours versus waiting 3 days. The goal was to see if early imaging improves survival at 30 days. P…

This study observed how emergency medical teams give breaths to adults suffering cardiac arrest outside the hospital. Using a portable device, researchers measured the volume, frequency, and pressure of ventilations during CPR. The goal was to describe current practices, not to t…

This study looked at how a 250 mg caffeine pill (about 2-3 cups of coffee) affects anxiety, decision-making, and body awareness in 42 people—some with panic disorder and some healthy. Participants took caffeine or a placebo on different days while having their brain scanned in a …

This study looked at 676 children in Swedish pediatric intensive care units (PICUs) to find out how often delirium occurs and what factors increase the risk. Delirium is a sudden change in mental state causing confusion or trouble paying attention. The researchers used a simple s…

This completed study looked at 164 women with and without fibromyalgia to see if certain autoantibodies are linked to more severe symptoms. Researchers compared patients with high and low antibody levels, and healthy controls, using questionnaires, blood tests, skin biopsies, and…

This study looked at 380 adults in the intensive care unit with suspected or confirmed COVID-19. Researchers tracked organ problems like kidney injury and lung failure, and measured survival rates at 30 days and one year. The goal was to learn how COVID-19 causes organ damage, no…

This study looked at whether a balance test called the Mini-BESTest is a reliable tool for people with long-term pain. Researchers tested 73 adults with chronic non-cancer pain and also interviewed some about their balance experiences. The goal was to understand how well the test…