Uppsala University

This study tests whether giving two strong medications one after the other—rituximab then cladribine—is safe and works well for people with relapsing-remitting multiple sclerosis (MS). Sixty adults aged 18 to 50 with active MS within the last year will receive the treatment and b…

This study compares two types of back surgery for teens and young adults with scoliosis (a curved spine). One is the standard open surgery, and the other is a newer, minimally invasive approach that uses smaller cuts and advanced imaging. The goal is to see if the less invasive m…

This study tests whether extra dental care every three months for three years can prevent or reduce late side effects like dry mouth, cavities, and jaw stiffness in head and neck cancer survivors. 300 adults who completed radiation or chemoradiation will either get this extra sup…

This study tests a program called EMBER-IPV, designed to help women use their inner strengths to recover after intimate partner violence. About 150 women who experienced abuse in the past two years will fill out questionnaires before, during, and after the program to track change…

This study compares three online treatments for people with clinical burnout who are on sick leave or struggling at work. 210 adults in Sweden will receive either acceptance and commitment therapy (ACT), a recuperation-focused program, or ACT plus extra work support. The goal is …

This study tests a program called EMBER designed to help women who have experienced intimate partner violence build resilience and improve their well-being. Eight women will take part in the program and answer weekly questionnaires about their resilience and health. Researchers w…

This observational study will collect blood samples from 25,000 adult ICU patients in Sweden to look for genetic variants linked to severe illness from infections, sepsis, or organ failure. Participants also give samples 3-6 months after leaving the hospital. The goal is to build…

This study looks at whether a skin monitor can reliably measure pain in newborns after surgery. Since babies can't tell us they're in pain, doctors currently use checklists and vital signs. The monitor tracks skin conductance, a sign of stress. Researchers will compare it to stan…

This trial in a Tanzanian refugee camp will test two programs for caregivers: a stress management course (Self Help Plus) and a parenting class (ICC-P). Researchers want to see if these programs improve children's emotional and behavioral health. About 324 families with children …