Massive DNA hunt aims to predict who gets critically ill

NCT ID NCT07582601

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study will collect blood samples from 25,000 adult ICU patients in Sweden to look for genetic variants linked to severe illness from infections, sepsis, or organ failure. Participants also give samples 3-6 months after leaving the hospital. The goal is to build a national biobank to help understand why some people become critically ill and to prepare for future pandemics.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help identify people at higher genetic risk for critical illness, potentially guiding future prevention or early treatment strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not find clear genetic links, and results may not apply outside Sweden.

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Conditions

The condition(s) this trial relates to.

acute kidney injury acute lung injury Critical Illness heart failure Infections Sepsis Shock

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••