University Of Sao Paulo General Hospital

This study is testing a live attenuated dengue vaccine (Butantan-DV) in 477 people aged 12–59 with stable autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) and in healthy volunteers. The goal is to see if the vaccine is safe and produces a strong immune response …

This study is testing whether a non-invasive chest monitor called electrical impedance tomography (EIT) can accurately diagnose pulmonary hypertension, a serious lung condition. Currently, diagnosis requires an invasive procedure called right heart catheterization. The study will…

This study tests the shingles vaccine in 200 adults with autoimmune rheumatic diseases (like rheumatoid arthritis or lupus) who are taking immune-suppressing drugs. The goal is to see if the vaccine triggers a strong immune response and prevents shingles. Participants will receiv…

This study tests two treatments for vaginal dryness in women with Sjögren's disease: a special laser and a topical hormone cream. About 60 women will be randomly assigned to one of the two treatments. The goal is to see which approach better improves vaginal health and sexual fun…

This study is looking at why people with pulmonary arterial hypertension (PAH), a rare and serious lung disease, often wait a long time for a correct diagnosis. Researchers will review medical records from 139 adults in Brazil to see how many doctors they saw and what tests were …

This study compares two video laryngoscopes—the McGRATH™ MAC and the BESDATA BD-DF—for placing breathing tubes in infants during surgery. About 226 children aged 6 months to 3 years will be randomly assigned to one device. The goal is to see if the BESDATA works as well as the Mc…

This study is creating and testing a questionnaire to see how much people with pulmonary arterial hypertension (PAH) know about their condition. Researchers will check if the questions make sense to patients and experts. Up to 200 adults with PAH will take part. The goal is to ha…

This study looks at whether tiny particles released by cells into the blood, called extracellular vesicles, can help detect a rare heart condition called ATTR amyloidosis earlier. The disease is often found only after significant heart damage has occurred. Researchers will compar…