University Of Sao Paulo General Hospital

This study looks at whether temporarily stopping methotrexate (a common arthritis drug) for two weeks after getting the PCV20 pneumonia vaccine can help the vaccine work better in adults with autoimmune rheumatic diseases like rheumatoid arthritis or lupus. About 192 participants…

This study tests whether giving a single dose of amoxicillin before a simple tooth extraction can prevent infections in people with autoimmune rheumatic diseases who take immune-suppressing drugs. About 352 adults will be randomly assigned to receive either the antibiotic or a pl…

This study compares a digital game to a traditional lecture for teaching burn prevention and first aid to 44 students. Participants will take a knowledge test before and after the lesson, and again two weeks later. The goal is to see which method helps young people learn and reme…

This study will test a smartphone app called CONEMO in 12,400 adults visiting primary care clinics for depression, anxiety, or insomnia. The app has already shown it can help with depression. Researchers want to see if it also improves anxiety and sleep problems. Participants wil…