Pausing arthritis drug may boost pneumonia vaccine power
NCT ID NCT07242092
First seen Nov 21, 2025 · Last updated Apr 28, 2026 · Updated 20 times
Summary
This study looks at whether temporarily stopping methotrexate (a common arthritis drug) for two weeks after getting the PCV20 pneumonia vaccine can help the vaccine work better in adults with autoimmune rheumatic diseases like rheumatoid arthritis or lupus. About 192 participants with stable, low-disease activity will be randomly assigned to either pause methotrexate or continue it. Researchers will measure antibody levels and check for disease flare-ups.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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