University Of Melbourne

This study tests a drug called tenecteplase for people having a severe stroke caused by a blockage in the basilar artery at the back of the brain. Participants receive either standard care or tenecteplase within 24 hours of symptoms, followed by a procedure to remove the clot if …

This study tests whether a new, less invasive surgery to remove blood clots from the brain within 8 hours of a stroke can improve recovery compared to standard medical care. About 240 adults with a large brain bleed will be randomly assigned to either the new surgery or usual tre…

This large international trial is testing different treatments to lower the risk of death in people with a serious staph bloodstream infection. Up to 8,000 hospitalized adults will receive one of several experimental therapies. The main goal is to see which treatments improve sur…

This study is testing whether a single low dose of nivolumab, a drug used in cancer treatment, can reduce the hidden HIV reservoir in people living with HIV who are on antiretroviral therapy (ART). The HIV reservoir is a group of infected cells that stay dormant and prevent a cur…

This study compares two online treatments for Irritable Bowel Syndrome (IBS): a low-FODMAP diet program that limits certain carbohydrates, and exposure-based cognitive behavioral therapy (E-CBT) that helps change unhelpful behaviors. Researchers will track 235 adults in Australia…

This study is for adults with hay fever living in South-Eastern Australia. Researchers want to find out who is most at risk for thunderstorm asthma, a dangerous condition that can occur during spring pollen season. Participants will be tested for grass pollen allergy, do simple b…