University Of Liverpool

This study tested whether the drug dapagliflozin (Forxiga) works better than standard treatments for people with type 2 diabetes whose blood sugar is not well controlled on metformin alone. Over 600 adults took either dapagliflozin plus metformin or usual care (like sulfonylureas…

This study looked at whether the HIV drug dolutegravir is safe and effective in pregnant women who have not yet been treated for HIV. Sixty women in late pregnancy were randomly assigned to receive either dolutegravir or standard HIV medicines. The goal was to measure drug levels…

This study looked at new markers in blood and urine to detect and predict the severity of drug-associated acute pancreatitis in adults. Researchers compared these markers in 175 patients with drug-induced pancreatitis, other pancreatic diseases, and healthy volunteers. The goal i…

This study looked at whether using CT scans and a rapid sputum test (FilmArray) can improve diagnosis of hospital-acquired pneumonia (HAP). Currently, chest X-rays are often unclear, leading to misdiagnosis and overuse of antibiotics. The trial enrolled 220 adults with suspected …

This study in Blantyre, Malawi, compares two schedules of the pneumococcal conjugate vaccine (PCV13): the current 3-dose schedule without a booster (3+0) versus a 2-dose schedule with a booster at 9 months (2+1). The goal is to see if the booster reduces carriage of vaccine-type …

This early-stage study tested a new drug called APPA-1 in 40 healthy volunteers and people with osteoarthritis. The main goal was to see if the drug is safe and how the body processes it. Researchers also looked at how food and gender affect the drug. This is a first step to see …

This study tested whether a gel called PuraBond, applied to the surgical wound during mouth or throat surgery, can reduce pain and bleeding afterward. 73 patients were randomly assigned to receive the gel or not. Researchers measured pain levels over 30 days and tracked complicat…

This completed online trial tested whether adding Nutri-Score labels (A to E, like a nutrition grade) to delivery app menus helps people choose healthier meals. 870 adults who regularly use food delivery apps made hypothetical meal choices in a simulated app. The study compared t…

This completed observational study followed 168 pregnant or breastfeeding women with schizophrenia, psychosis, or mania who were already taking long-acting injectable antipsychotics. Researchers measured drug levels in the mother's blood, breastmilk, and the baby's blood to under…

This study tested whether adding Nutri-score labels (A to E ratings) to restaurant menus, alongside calorie information, helps people pick healthier meals. Over 600 adults in Liverpool ordered from a menu with either calorie info alone or calorie info plus Nutri-score labels. Res…

This study tested whether showing calorie information on alcohol or reducing serving sizes can lower how much people drink. Over 300 regular drinkers took part in a real-world pub quiz setting. Researchers measured alcohol units and total calories consumed during the evening.

This study looked at whether people with type 2 diabetes need to attend all sessions of a diabetes self-management education program to see benefits. 120 participants were split into groups that attended 100%, 60%, 10%, or no education. Researchers measured changes in self-care, …