New tests aim to cut unnecessary antibiotics for lung infections in hospitals

NCT ID NCT05483309

Completed Diagnosis Sponsor: University of Liverpool Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at whether using CT scans and a rapid sputum test (FilmArray) can improve diagnosis of hospital-acquired pneumonia (HAP). Currently, chest X-rays are often unclear, leading to misdiagnosis and overuse of antibiotics. The trial enrolled 220 adults with suspected HAP to see if these modern tests could help doctors give the right antibiotics faster. Since this is a feasibility study, its main goal was to see if a larger, more definitive trial is possible.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CT scan and FilmArray Pneumonia Panel (rapid sputum test)
What this could lead to: If successful, this could lead to a larger trial that shows how to diagnose hospital-acquired pneumonia more accurately, reduce unnecessary antibiotics, and slow antibiotic resistance.
What could go wrong: This is a small feasibility study, not a full trial. It only checks if a larger trial is possible, so it won't directly prove that these tests improve patient outcomes.

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Conditions

The condition(s) this trial relates to.

Healthcare-Associated Pneumonia nosocomial infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HOSPITAL-ACQUIRED PNEUMONIA

Contacts and locations

Locations

Lancashire teaching hospitals NHS Foundation Trust

Preston, United Kingdom
Liverpool University Hospitals NHS Foundation Trust

Liverpool, L69 7BE, United Kingdom
Manchester University NHS Foundation Trust

Manchester, United Kingdom

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