University Of Cologne

This study tests whether dapagliflozin, a drug used for diabetes, can slow the loss of kidney function in people with autosomal dominant polycystic kidney disease (ADPKD). ADPKD is the most common inherited cause of kidney failure, and the only approved treatment often causes sev…

This study will follow 1,000 immunocompromised patients, including those with blood cancers, to see how their immune systems respond to vaccines against respiratory viruses like flu and COVID-19. Researchers will measure both antibody levels and T cell responses, which may offer …

This study looks at whether placing a moderate or late preterm baby directly on the mother's skin right after vaginal birth can reduce stress and improve development. Researchers will compare babies who get immediate skin-to-skin contact with those who are separated briefly. The …

This study looks at how different diets—like a fasting-mimicking diet, a ketogenic diet, or a diet low in certain amino acids—change the biology of kidney tissue in people about to donate a kidney. Researchers will take small tissue samples before and after the diet to measure pr…

This study is a global registry that collects information from 200 people with hantavirus infections. Researchers aim to track how the disease spreads, its symptoms, complications, and treatments used. No new treatments are tested; the goal is to gather knowledge to improve futur…

This study watches how the body manages water and salt in people being treated for low sodium levels (hyponatremia). Researchers will measure blood and urine changes over time in 50 adults. The goal is to better understand the treatment process, not to test a new drug.

This study is creating a global registry to track leptospirosis, a bacterial disease spread by animals. Researchers will collect data from 200 people with confirmed or suspected infections to learn how the disease behaves, what treatments work, and how often it leads to serious c…

This study looks at how people with end-stage kidney disease manage sodium levels when given extra water or salt. Researchers want to test if current theories about sodium balance hold true in these patients. The goal is to better understand hyponatremia (low sodium), a common an…