University Of Cologne

This study is testing whether the medication dapagliflozin can slow the loss of kidney function in adults with autosomal dominant polycystic kidney disease (ADPKD), a genetic condition that often leads to kidney failure. The trial will enroll 420 participants who show signs of ra…

This study aims to understand how the bodies of people with severe kidney failure handle changes in sodium and water levels. Researchers will give 60 participants on stable dialysis either an intravenous water or salt solution and measure how sodium moves inside and outside their…

This study is creating a global registry to gather information on hantavirus infections, which can cause serious kidney and lung diseases. It aims to understand how the disease spreads, its symptoms, and what factors affect patient outcomes. The goal is to use this knowledge to i…

This study is creating a worldwide registry to better understand severe leptospirosis, a serious bacterial infection spread by animals. Researchers will track 200 patients with confirmed or suspected severe cases to learn how the disease spreads, how it affects people, and what f…

This study aims to better understand how the body's water and salt levels change when treating a condition called low blood sodium (hyponatremia). Researchers will closely monitor 50 adult patients with this condition, measuring things like blood and urine composition, body water…

This study is investigating whether immediate skin-to-skin contact between a mother and her preterm baby after birth can influence the baby's stress-related genes and improve their development. Researchers will compare 60 preterm babies who receive this immediate contact with tho…