Can a Pre-Donation diet boost kidney health?

NCT ID NCT05709600

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at whether special diets—like a fasting-mimicking diet, a ketogenic diet, or a low-sulfur diet—can change the molecular makeup of kidney tissue before living donation. Researchers will analyze proteins, fats, and genetic material in kidney biopsies from 80 donors. The goal is to understand how diet might protect the kidney and improve transplant success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fasting mimicking diet (Prolon®), ketogenic diet, dietary restriction of sulfur-containing amino acids

What this could lead to

If successful, this could reveal how specific diets prepare kidneys for transplantation, potentially improving donor recovery and transplant outcomes.

What could go wrong

This is a small, early-stage study (80 participants) focused on molecular changes, not clinical outcomes. The diets may not produce meaningful differences, and results may not apply to all donors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Department II of Internal Medicine, Center for Molecular Medicine Cologne (CMMC), University Hospital of Cologne

    RECRUITING

    Cologne, 50931, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact