Scientists test how dialysis patients regulate sodium when given water or salt

NCT ID NCT06408077

Recruiting now Knowledge-focused Sponsor: University of Cologne Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at how the body controls sodium levels in people with end-stage kidney disease who are on dialysis. Researchers will give participants either water or a concentrated salt solution to see how their sodium levels change. The goal is to better understand hyponatremia, a common and dangerous electrolyte disorder, and improve treatment for these patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Water and sodium chloride (salt) solution
What this could lead to: If successful, this could improve how doctors predict and manage sodium imbalances in kidney patients, potentially reducing complications like brain swelling.
What could go wrong: This is a small, early-stage study with only 60 participants, so results may not apply to all patients. The interventions carry risks like fluid overload or rapid sodium changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

end stage renal failure Hyponatremia Water-Electrolyte Imbalance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPONATREMIA

Contacts and locations

Locations

Department II of Internal Medicine,University of Cologne
RECRUITING

Cologne, 50937, Germany

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