University Hospital Schleswig-holstein

This study tests whether a special form of vitamin B3 (nicotinamide) can help people with mild to moderate ulcerative colitis. About 459 adults will take either a low dose, high dose, or placebo pill for several weeks. The goal is to see if it reduces gut inflammation and improve…

This study compares two treatment approaches for people newly diagnosed with moderate-to-severe ulcerative colitis (UC). One group gets early treatment with mirikizumab, a biologic drug, while the other starts with standard azathioprine pills and can switch to mirikizumab later i…

This study tests whether tralokinumab, an approved eczema drug, can improve moderate-to-severe atopic dermatitis in the genital area. About 30 adults will receive the drug and be monitored for 52 weeks using special skin imaging and symptom questionnaires. The goal is to see if i…

This study tests a new, shorter radiation treatment for men with early-stage prostate cancer. Instead of the usual 5 sessions, it uses only 3 sessions of high-dose radiation. The goal is to see if this approach causes fewer long-term side effects while still controlling the cance…

This study tests a new pill (CIR-NA) that releases nicotinic acid in the gut to see if it can stop prediabetes from turning into type 2 diabetes. About 390 adults with prediabetes will take the pill or a placebo daily for 26 weeks, along with lifestyle advice. The goal is to see …

This study follows 100 women who had preeclampsia, HELLP syndrome, or kidney disease during pregnancy to monitor their heart and kidney health over time. Researchers will measure blood vessel stiffness and collect blood samples for a biobank. The goal is to better understand long…

This study aims to find people who may be at higher risk for Parkinson's disease before symptoms appear. Researchers will screen 2,000 adults aged 50 to 99 and follow them for five years to track changes in risk markers and early symptoms. The goal is to better understand how the…

This study looks at why many people with Parkinson's disease crave sugary foods and how those sugars affect their body and symptoms. Researchers will give 50 participants a sugary drink and a placebo drink on different days to measure changes in insulin, blood sugar, and movement…