New hope for UC patients: early biologic treatment may beat standard therapy

NCT ID NCT07235904

First seen Nov 19, 2025 · Last updated Jun 13, 2026 · Updated 24 times

Summary

This study compares two treatment approaches for people newly diagnosed with moderate-to-severe ulcerative colitis (UC). One group gets early treatment with mirikizumab, a biologic drug, while the other starts with standard azathioprine pills and can switch to mirikizumab later if needed. The goal is to see if starting with mirikizumab leads to better disease control and fewer side effects over 52 weeks. About 300 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospital Schleswig-Holstein

    RECRUITING

    Kiel, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.