University Hospital, Bonn

This study tests whether giving immunotherapy and chemotherapy before surgery or radiation, followed by more immunotherapy, can help people with stage III lung cancer live longer without the cancer coming back. About 176 adults with resectable or borderline resectable non-small c…

This study tests whether increasing physical activity through a motivational smartphone app can slow cognitive decline in people with isolated REM sleep behavior disorder (iRBD), an early sign of Parkinson's disease and related disorders. Researchers will enroll 130 participants …

This study tests whether using blood flow restriction cuffs during low-intensity stationary cycling can safely improve muscle strength and mobility in older adults recovering from a hip fracture. Sixty hospitalized patients over age 65 will be randomly assigned to either real or …

This study tests whether adding strength training with blood flow restriction to standard rehab helps people who had a hip replacement 4 weeks ago. 30 participants will do either regular exercise therapy or the same therapy plus the special strength training. Researchers will mea…

This study tests whether combining light strength training with blood flow restriction (BFR) can help people rebuild muscle and strength after anterior cruciate ligament (ACL) surgery. Thirty participants will do daily BFR training for about 25 minutes as part of their outpatient…

This pilot study aims to see if a new method can safely measure how tired patients get during a special type of exercise after total knee replacement. Twenty adults recovering from knee surgery will try cycling while blood flow to their legs is partially restricted. The results w…

This study uses a technique called microdialysis to measure antibiotic levels directly inside the hip joint after surgery for an infected hip replacement. Researchers want to see how well local antibiotics from a cement spacer work and compare them to levels in the blood. The goa…

This study uses a technique called microdialysis to measure antibiotic levels inside the knee joint after surgery for a knee replacement infection. Researchers will place a tiny probe in the joint to collect fluid samples during the hospital stay (about 14 days). They want to see…