Universitätsklinikum Hamburg-eppendorf

This early-stage trial tested a new two-part vaccine designed to treat chronic hepatitis B. It involved 26 healthy adults to check safety and immune response. The vaccine uses a protein first shot followed by a booster to teach the immune system to attack the virus.

This completed trial tested whether inflatable leg sleeves (pneumatic compression) could reduce the amount of norepinephrine, a drug that raises blood pressure, needed during non-cardiac surgery. 238 adults aged 45 and older were randomly assigned to receive either the leg sleeve…

This large international trial tested whether keeping a patient's blood flow (cardiac index) at their own personal baseline during major abdominal surgery reduces serious complications. Over 1,100 high-risk adults aged 45 and older took part. The goal was to see if this personali…

This study tested a short-term talking therapy (psychodynamic psychotherapy) for 24 adults with advanced solid tumors and high psychological distress. The goal was to see if the therapy is safe, acceptable, and feasible, not to cure the cancer. Results will help design larger stu…

This study tested whether a nerve block (serratus anterior plane block) can reduce pain and the need for strong painkillers after minimally invasive mitral valve repair. 78 adults having this heart surgery were randomly assigned to receive either the nerve block or a placebo. The…

This study tests a device that synchronizes two types of brain stimulation — deep brain stimulation (DBS) and transcranial alternating current stimulation (tACS) — in people with Parkinson's disease. Only 2 participants will be enrolled to see if the device can lock the timing of…

This completed study looked at how rising temperatures affect people with chronic conditions like heart disease, diabetes, and depression. Researchers in Germany and Italy surveyed 176 patients to see what symptoms they experienced during heat and what protective steps they took.…

This study tested whether a gentle, non-invasive brain stimulation technique called tDCS, applied over the cerebellum, can change brain activity and reduce symptoms in people with cervical dystonia (neck muscle spasms). Fifteen participants received real and sham (fake) stimulati…

This study looked at 56 adults with fully remitted depression who wanted to stop their antidepressant. Researchers wanted to see how much of the withdrawal symptoms are caused by the drug itself versus the person's expectations. Participants were randomly assigned to either stop …

This study tested whether a gentle, non-invasive brain stimulation technique called tACS could improve hand function in 20 stroke survivors. The stimulation targeted two key brain areas involved in movement planning. Researchers measured brain connectivity and hand movement patte…

This study tested whether a continuous finger-cuff blood pressure monitor could reduce episodes of low blood pressure during non-cardiac surgery compared to the standard arm cuff that measures blood pressure every few minutes. The trial included 930 low-to-moderate risk adults ha…

This registry collected information and biological samples from 354 children and young adults diagnosed with certain brain tumors like medulloblastoma and ependymoma. The goal was to improve diagnostic standards through expert review and to gather data for future research. No new…

This study tested a German version of a questionnaire that measures how well parents and their children (ages 10-18) communicate. Over 2,300 families participated, and researchers checked if communication quality was linked to teens' physical symptoms and mental health. Two years…

This study looked at two non-invasive methods (NIRS and TCD) to monitor how well the brain controls its own blood flow during major non-cardiac surgery. The goal was to see which method works better and whether keeping blood pressure in a certain range can reduce the risk of conf…