Tianjin Medical University General Hospital

This study tests whether giving a large amount of IV saline (about 2-2.5 liters) right after clot-busting treatment helps people recover from a stroke better than giving only a small amount. The trial will enroll 752 adults aged 18-80 who had an ischemic stroke and received throm…

This early-stage trial will test whether infusing a patient's own tumor-fighting immune cells (called TILs) is safe for people with early-stage non-small cell lung cancer that has multiple spots in the lungs. Researchers will collect immune cells from the tumor or lung fluid, gro…

This early-phase trial tests whether combining a patient's own immune cells (called TILs) with a targeted therapy drug can safely treat advanced lung cancer that has stopped responding to standard targeted treatment. Researchers will enroll 50 adults with EGFR-mutant non-small ce…

This study tests whether roxadustat, a drug currently used to treat anemia in kidney disease, can also improve sarcopenia (muscle loss) in patients on hemodialysis. Sixty adults with end-stage kidney disease and anemia will receive either roxadustat or standard erythropoietin. Re…

This study tests whether a low dose of esketamine, given during knee replacement surgery, can reduce itching in elderly patients with senile pruritus. Two hundred participants will receive either esketamine or a placebo, and their itching will be measured over the following week.…

This study tests whether giving a single intravenous dose of esketamine during a C-section can reduce the intense itching that often follows surgery in women with intrahepatic cholestasis of pregnancy. 160 women will be randomly assigned to receive either esketamine or a placebo …

This study tests if a painkiller called oliceridine can prevent long-term pain after lung surgery better than the usual drug, sufentanil. About 320 adults having keyhole lung surgery will receive one of the two drugs through a pump they control. The main goal is to see if fewer p…