The University Of Tennessee, Knoxville
Clinical trials sponsored by The University Of Tennessee, Knoxville, explained in plain language.
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New diet strategy: eat more Low-Cal foods to maintain weight loss
Disease control CompletedThis study tested whether a diet focused on low-energy-density foods (like fruits, vegetables, and broth-based soups) helps people maintain weight loss better than simply counting calories. 345 adults with obesity were followed for 22 months. Researchers measured changes in weigh…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Could a Brain-Healthy diet help fight ALS and Parkinson's?
Disease control CompletedThis study tested whether people with ALS or Parkinson's disease, along with healthy volunteers, could follow the MIND diet — a mix of the Mediterranean and DASH diets thought to protect the brain. Over several weeks, 43 participants received a cookbook, educational materials, an…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Small study explores ways to boost sexual wellness after breast cancer
Symptom relief CompletedThis study looked at whether it's possible to test a program that combines different approaches to help breast cancer survivors with sexual health issues. 18 women who had finished their main cancer treatment took part. The goal was to see if women would join, stay, and follow th…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Morning or evening walk? study finds best time to exercise for gestational diabetes
Symptom relief CompletedThis study looked at whether exercising in the morning or evening helps control blood sugar better in pregnant women with gestational diabetes or glucose intolerance. 39 women walked or stepped for 30 minutes either after breakfast or after dinner. The researchers measured blood …
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Text therapy shows promise for anxious young adults
Symptom relief CompletedThis study tested whether an 8-week automated text-message therapy program could reduce anxiety in young adults aged 18-25. One hundred participants with elevated anxiety were randomly assigned to receive the text therapy or be placed on a waitlist. The goal was to see if this co…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Scientists compare three knee implant designs to see which moves most naturally
Knowledge-focused CompletedThis study looks at how three types of Journey II knee replacements (BCS, CR, and XR) move inside the body during activities like bending. Researchers will use video and sound recordings to measure joint motion in people who had knee replacement surgery at least six months ago. T…
Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Gum before ice cream: a trick to eat less?
Knowledge-focused CompletedThis study looked at whether chewing gum before eating ice cream affects how much people eat. Twenty normal-weight adults who liked mint chocolate chip ice cream took part. They either chewed mint, cinnamon, or no gum before a computer task where they earned ice cream. The main g…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Study explores link between diet variety and Post-Surgery weight loss
Knowledge-focused CompletedThis study looked at 90 adults who had bariatric surgery to see if changing the variety of foods they ate affected their food cravings, calorie intake, and weight loss over 12 months. Researchers tracked participants' diets to understand patterns that might help improve long-term…
Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Study reveals: mixing veggies into pasta may change your meal intake
Knowledge-focused CompletedThis study looked at how serving vegetables mixed into pasta or on the side affects how much normal-weight adults eat. Forty-five participants ate pasta with zucchini and squash presented in three different ways. Researchers measured how much pasta and vegetables were eaten, alon…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Does when you eat matter? study investigates eating frequency and weight loss
Knowledge-focused CompletedThis study looked at how often people eat and whether it affects weight loss. Researchers followed 30 overweight adults aged 18 to 65. They tracked eating habits, calories, and weight to better understand the link between meal timing and losing weight.
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Grazing vs. meals: which keeps you from overeating?
Knowledge-focused CompletedThis study looked at whether eating three meals a day or grazing (eating small amounts every 2-3 hours) changes how much people eat at an evening meal and their total daily calorie intake. Twenty healthy adults aged 18-35 with normal weight tried both eating patterns. Researchers…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Study tests if filling up on Low-Cal foods boosts weight loss
Knowledge-focused CompletedThis study looked at whether eating foods with fewer calories per bite (low energy density) helps people lose weight. Sixty adults with overweight or obesity followed a 12-week lifestyle program. Researchers tracked what they ate, how full they felt, and weight changes to find th…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Researchers watch how active people move
Knowledge-focused CompletedThis study looked at how normal to overweight adults who are already regularly active vary their physical activities and where they do them. About 50 participants wore an armband to track their movement. The goal was simply to describe patterns, not to test any treatment.
Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Can changing what you say about food improve your Family's health?
Knowledge-focused CompletedThis study looked at how three different types of dietary advice affect what families eat and their overall health. It involved 45 families with an overweight parent and a child aged 6-12 who was at a healthy weight. Researchers measured changes in diet, body measurements, and pa…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Snack study: do extra treats make tots eat more?
Knowledge-focused CompletedThis small pilot study looked at whether giving snacks to preschoolers changes how many calories they eat overall. Twenty children aged 3 to 5 were given snacks either as part of their daily calorie needs or in addition to them. Researchers measured total calories from food and d…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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New teacher training shows promise for deaf education
Knowledge-focused CompletedThis study looked at whether a professional development program helps teachers of deaf students use a specific signing instruction method more accurately. Four teachers participated, and researchers checked how well they followed the program using a detailed checklist. The goal w…
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Gamifying diet logs: a small study tests if rewards boost Kids' tracking
Knowledge-focused CompletedThis study tested whether adding praise from parents and game-like features (points, levels, a virtual pet) to a digital food log helps children aged 8-12 track their eating more often. Nineteen children and their caregivers participated for 4 weeks. The goal was to see if these …
Phase: NA • Sponsor: The University of Tennessee, Knoxville • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC