The Methodist Hospital Research Institute

This early-phase trial tested whether adding L-NMMA to the immunotherapy drug pembrolizumab is safe for people with several types of advanced cancer. The idea is that L-NMMA may remove a brake on the immune system, helping pembrolizumab work better. Only 12 adults took part, and …

This early-stage trial tested whether a combination of two drugs, abatacept and interleukin-2, is safe for people with ALS. The goal was to increase the number and activity of regulatory T cells, which are immune cells that may help slow disease progression. Five participants wer…

This study tested whether giving blood plasma from people who recovered from COVID-19 to those with severe or critical COVID-19 is safe and helpful. 350 adults received the plasma treatment. The main goals were to track serious side effects and survival rates at 28 days.

This study tested two different contrast agents (Dotarem and Gadovist) used during heart MRI scans to see if they produce equally clear images. 120 adults with coronary artery disease or cardiomyopathy were randomly assigned to receive one of the two agents. The goal was to compa…

This small study tested whether electro-acupuncture (a gentle electric current through needles) could help people with nerve pain caused by chemotherapy. Twenty adults who had finished chemo at least 3 months prior received 10 treatments. The main goal was to see if the treatment…

This study tested a non-invasive brain stimulation technique called rTMS in 14 adults with overactive bladder. The goal was to see if it could change brain activity and improve bladder symptoms like urgency and frequent urination. Researchers used brain scans to measure changes, …

This study tested whether a virtual reality (VR) program called ReCognitionVR is safe and acceptable for older adults recovering from abdominal surgery. Thirty patients aged 60 and older used the VR software or received standard orientation methods. The goal was to see if VR coul…