The Methodist Hospital Research Institute
Clinical trials sponsored by The Methodist Hospital Research Institute, explained in plain language.
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New gene therapy tested for Tough-to-Treat lung cancer
Disease control TerminatedThis early-stage study tested the safety of combining an existing immunotherapy drug (atezolizumab) with a new gene therapy (ADV/IL-12) for patients with advanced non-small cell lung cancer. The trial was for people whose cancer had continued to grow despite receiving standard fi…
Phase: PHASE1 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Gene therapy joins fight against tough breast cancer
Disease control TerminatedThis study tested a combination of three treatments for an aggressive type of breast cancer that had stopped responding to standard chemotherapy. It combined chemotherapy (docetaxel), an immunotherapy drug (pembrolizumab), and an experimental gene therapy designed to boost the im…
Phase: PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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Can simple exercises beat standard knee pain treatment?
Symptom relief TerminatedThis study tested if a specific set of knee-strengthening exercises (called a knee isometric program) worked better than the usual physical therapy for reducing pain in the front of the knee. A small group of adults with knee pain were randomly assigned to try one of the two exer…
Phase: NA • Sponsor: The Methodist Hospital Research Institute • Aim: Symptom relief
Last updated Mar 24, 2026 12:01 UTC
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Doctors track Kids' reactions to Life-Saving rabies shot
Knowledge-focused TerminatedThis study observed children (age 17 and under) who received a standard rabies prevention shot after an animal bite or scratch. Researchers tracked any side effects for 30 days to confirm the shot's safety in kids. The study did not test a new treatment but monitored the safety o…
Sponsor: The Methodist Hospital Research Institute • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC