The Methodist Hospital Research Institute
Clinical trials sponsored by The Methodist Hospital Research Institute, explained in plain language.
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Experimental combo targets lung cancer that resists immunotherapy
Disease control TerminatedThis early-stage trial tested a combination of two treatments—atezolizumab (an immunotherapy drug) and interleukin-12 gene therapy (which uses a virus to deliver a gene that boosts the immune system)—in 13 people with advanced non-small cell lung cancer that had worsened after in…
Phase: PHASE1 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Experimental triple combo for tough breast cancer shows early promise but trial stops short
Disease control TerminatedThis Phase 2 trial tested a combination of chemotherapy (docetaxel), an immunotherapy drug (pembrolizumab), and a gene therapy (IL-12) in 8 women with triple negative breast cancer that had stopped responding to standard anthracycline treatment. The goal was to see if the combina…
Phase: PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Knee pain relief through isometric exercises? small study halted early
Symptom relief TerminatedThis study looked at whether a specific set of isometric (holding still) exercises could reduce pain and improve function in people with anterior knee pain. Only 6 people enrolled before the study was stopped early. Participants did exercises like wall sits and glute bridges, and…
Phase: NA • Sponsor: The Methodist Hospital Research Institute • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Rabies treatment safety study in kids halted early
Knowledge-focused TerminatedThis study aimed to check the safety of a rabies immune globulin shot (HyperRAB) in children who were treated after an animal bite. It included 35 kids aged 17 and under across several emergency rooms. The study was stopped early, so results are limited, but the goal was to see i…
Sponsor: The Methodist Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC