The Methodist Hospital Research Institute
Clinical trials sponsored by The Methodist Hospital Research Institute, explained in plain language.
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Triple threat: new combo tackles stubborn breast cancer
Disease control TerminatedThis study tested a mix of chemotherapy (docetaxel), an immunotherapy drug (pembrolizumab), and a gene therapy (IL-12) in 8 women with a tough-to-treat type of breast cancer that had stopped responding to standard treatment. The goal was to see if this combination could shrink or…
Phase: PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated May 17, 2026 04:43 UTC
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Experimental combo targets lung cancer that resists initial treatment
Disease control TerminatedThis early-phase study tested a combination of an immunotherapy drug (atezolizumab) and a gene therapy (IL-12) in 13 people with advanced non-small cell lung cancer that had worsened after initial immunotherapy. The goal was to see if the combination was safe and could help contr…
Phase: PHASE1 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated May 11, 2026 20:46 UTC
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Knee pain exercise study halted early – small trial shows little impact
Symptom relief TerminatedThis study aimed to see if a specific knee exercise program could reduce pain and improve function in people with anterior knee pain. It compared the program to standard physical therapy. Only 6 people enrolled before the study was stopped early, so results are very limited.
Phase: NA • Sponsor: The Methodist Hospital Research Institute • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Rabies shot safety study in kids halted early
Knowledge-focused TerminatedThis study aimed to check the safety of a rabies immune globulin product (HyperRAB®) in children up to 17 years old who received it after an animal bite. Researchers planned to track side effects for up to 30 days. The study was stopped early, so only limited safety information w…
Sponsor: The Methodist Hospital Research Institute • Aim: Knowledge-focused
Last updated May 17, 2026 04:17 UTC