Experimental combo targets lung cancer that resists initial treatment

NCT ID NCT04911166

First seen Mar 24, 2026 · Last updated May 08, 2026 · Updated 6 times

Summary

This early-phase study tested a combination of an immunotherapy drug (atezolizumab) and a gene therapy (IL-12) in 13 people with advanced non-small cell lung cancer that had worsened after initial immunotherapy. The goal was to see if the combination was safe and could help control the cancer. The study was terminated early, so results are limited.

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Contacts and locations

Locations

  • Houston Methodist Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.