The Methodist Hospital Research Institute
Clinical trials sponsored by The Methodist Hospital Research Institute, explained in plain language.
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Bone injection may beat IV for spine surgery infections
Disease control Not yet recruitingThis study compares two ways of giving the antibiotic vancomycin during lumbar fusion surgery: injecting it directly into the bone marrow versus the standard method through a vein. Researchers want to see which method delivers higher antibiotic levels to the bone and soft tissue,…
Phase: PHASE2, PHASE3 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Could stem cells restore erectile function after prostate surgery?
Disease control Not yet recruitingThis study tests whether stem cells from donated fat tissue can help men recover erectile function after surgery for localized prostate cancer. Forty men aged 40 to 70 will receive either stem cells or a placebo during or after their prostate removal. The goal is to see if the tr…
Phase: PHASE1, PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New blood test could personalize AML treatment
Diagnosis Not yet recruitingThis study tests a new blood test (5hmC) to see if it can help doctors choose between two standard treatments for acute myeloid leukemia (AML): a milder drug (hypomethylating agent) or strong chemotherapy. About 112 newly diagnosed adults will have their blood tested after initia…
Phase: PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Diagnosis
Last updated Jun 27, 2026 09:11 UTC
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Bone injection may boost antibiotic power in knee surgery
Knowledge-focused Not yet recruitingThis study tests whether giving the antibiotic vancomycin directly into the bone (via the ankle) works better than the usual IV method during revision knee replacement surgery. Forty adults having a second knee replacement will be randomly assigned to one of the two methods. Rese…
Phase: NA • Sponsor: The Methodist Hospital Research Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC