The Methodist Hospital Research Institute
Clinical trials sponsored by The Methodist Hospital Research Institute, explained in plain language.
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New antibiotic injection method tested for knee surgery
Disease control Not yet recruitingThis study aims to compare two different ways of giving antibiotics during revision knee replacement surgery. Researchers will test whether injecting antibiotics directly into the ankle bone works as well as giving them through an IV. The goal is to find the best method to help p…
Phase: NA • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Blood test could be key to picking winning leukemia treatment
Disease control Not yet recruitingThis study is testing whether a new blood test can help doctors choose the most effective chemotherapy for adults newly diagnosed with acute myeloid leukemia (AML). About 112 patients will receive one of two standard chemotherapy types, and the blood test will check for tiny amou…
Phase: PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Bone injection could beat IV for stopping spine infections
Disease control Not yet recruitingThis study is testing if putting an antibiotic directly into the bone during lower back fusion surgery works better than the usual method of giving it through a vein. Researchers will measure antibiotic levels in the bone, muscle, and blood of 30 patients to see which method deli…
Phase: PHASE2, PHASE3 • Sponsor: The Methodist Hospital Research Institute • Aim: Disease control
Last updated Mar 27, 2026 12:37 UTC
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Higher steroid dose tested to ease agony of kidney stents
Symptom relief Not yet recruitingThis study is testing if a higher dose of a common steroid (dexamethasone) can better reduce pain and bothersome urinary symptoms people often get after kidney stone surgery when a temporary internal tube, called a stent, is placed. Researchers will compare a high dose to a stand…
Phase: PHASE1, PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Stem cell shot aims to restore Men's sex lives after prostate cancer
Symptom relief Not yet recruitingThis study is testing whether stem cells can safely help men regain erectile function after surgery for prostate cancer. It will involve 40 men who are having a specific type of prostate removal surgery. Researchers will compare different methods and timings of giving stem cell i…
Phase: PHASE1, PHASE2 • Sponsor: The Methodist Hospital Research Institute • Aim: Symptom relief
Last updated Mar 23, 2026 15:14 UTC