The Methodist Hospital Research Institute

This Phase 1 trial tests a new type of cell therapy for people with relapsed or refractory CD30-positive lymphomas, including Hodgkin lymphoma and certain non-Hodgkin lymphomas. The treatment uses a patient's own immune cells that are genetically engineered to recognize and attac…

This study compares two ways of giving the antibiotic vancomycin during lumbar fusion surgery: injecting it directly into the bone marrow versus the standard method through a vein. Researchers want to see which method delivers higher antibiotic levels to the bone and soft tissue,…

This study tests a new blood test (5hmC) to see if it can help doctors choose between two standard treatments for acute myeloid leukemia (AML): a milder drug (hypomethylating agent) or strong chemotherapy. About 112 newly diagnosed adults will have their blood tested after initia…

This study tests whether giving the antibiotic vancomycin directly into the bone (via the ankle) works better than the usual IV method during revision knee replacement surgery. Forty adults having a second knee replacement will be randomly assigned to one of the two methods. Rese…