Swiss Cancer Institute

This study is for people with stage IIA or IIB seminoma, a type of testicular cancer. It tests a reduced-intensity combination of chemotherapy and radiation to see if it can control the cancer as well as standard treatment while causing fewer side effects. About 135 participants …

This study tests whether adding chest radiation to maintenance durvalumab can help people with extensive-stage small cell lung cancer live longer without the disease getting worse. About 46 participants will first receive standard chemo plus durvalumab, then those whose cancer re…

This phase 3 trial tests whether giving denosumab every 12 weeks is as effective as the standard every 4 weeks at preventing bone complications (like fractures or need for radiation) in people with metastatic breast or prostate cancer that has spread to the bone. About 1380 parti…

This study tests whether using ctDNA blood tests and PET scans can help doctors tailor treatment for people with diffuse large B-cell lymphoma (DLBCL). About 260 participants will receive standard chemotherapy (R-CHOP) plus or minus a targeted drug (acalabrutinib) based on their …

This trial tests whether giving a special BCG treatment directly into the bladder, followed by chemotherapy and immunotherapy, can make muscle-invasive bladder cancer disappear before surgery. The goal is to increase the chance of a complete response, so patients might avoid havi…

This study tests whether adding a special type of radiotherapy to standard chemotherapy and immunotherapy before surgery can improve outcomes for people with stage III lung cancer that has spread to lymph nodes. About 90 participants will receive one of three radiation schedules …

This study looks at whether a liquid biopsy (a test that looks for cancer DNA in spinal fluid) can find lymphoma in the brain more accurately than current methods. It involves 64 people with high-risk B-cell non-Hodgkin lymphoma. The goal is to improve detection and help doctors …