New combo aims to extend life in aggressive lung cancer

NCT ID NCT04472949

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests whether adding chest radiation to maintenance durvalumab can help people with extensive-stage small cell lung cancer live longer without the disease getting worse. About 46 participants will first receive standard chemo plus durvalumab, then those whose cancer responds will get chest radiation along with continued durvalumab for up to 2 years. The goal is to improve outcomes in a cancer that often returns quickly.

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Contacts and locations

Locations

  • HFR Freiburg - Kantonsspital

    Villars-sur-Glâne, 1752, Switzerland

  • Hôpitaux Universitaires de Genève

    Geneva, 1211, Switzerland

  • IOSI Ospedale Regionale di Bellinzona e Valli

    Bellinzona, 6500, Switzerland

  • Inselspital Bern

    Bern, 3010, Switzerland

  • Kantonsspital - St. Gallen

    Sankt Gallen, CH-9007, Switzerland

  • Kantonsspital Aarau

    Aarau, CH-5001, Switzerland

  • Kantonsspital Graubuenden

    Chur, CH-7000, Switzerland

  • Kantonsspital Olten

    Olten, CH-4600, Switzerland

  • Kantonsspital Winterthur

    Winterthur, 8401, Switzerland

  • Klinik Hirslanden

    Männedorf, 8708, Switzerland

  • Regionalspital Thun

    Thun, 3600, Switzerland

  • Spital Männedorf

    Männedorf, 8708, Switzerland

  • Universitaetsspital Basel

    Basel, 4031, Switzerland

  • UniversitätsSpital Zürich

    Zurich, 8091, Switzerland

Conditions

Explore the condition pages connected to this study.