Swedish Orphan Biovitrum

This study tested the drug emapalumab (Gamifant) in 13 Chinese patients with primary hemophagocytic lymphohistiocytosis (HLH), a rare and severe immune disorder. The goal was to see if the drug is safe and helps control the disease before a stem cell transplant. Researchers measu…

This study tested a drug called emapalumab in 33 children and adults with macrophage activation syndrome (MAS), a life-threatening immune overreaction, linked to Still's disease or lupus. The goal was to see if the drug could safely control the condition and reduce the need for h…

This study tested a new medicine called SEL-212 for people with chronic gout that doesn't get better with standard treatments. 153 adults received either one of two doses of SEL-212 or a placebo every 28 days for about 6 months. The goal was to see if the drug could lower uric ac…

This pilot study tested a drug called pegcetacoplan in 12 adults who developed a serious blood clotting condition (TA-TMA) after a stem cell transplant. The goal was to see how the drug moves through the body, if it helps, and if it is safe. Researchers measured drug levels and m…

This study tested a drug called pegcetacoplan in 24 adults with cold agglutinin disease, a rare condition where the immune system destroys red blood cells. Participants received either the drug or a placebo twice a week for 24 weeks. The goal was to see if the drug could raise he…

This study followed 151 people with hemophilia B who were already using or starting Alprolix, a long-lasting clotting factor. Over 24 months, researchers tracked how often bleeding occurred, how often the drug was injected, and how much was used. The goal was to see how well Alpr…

This Phase 3 trial tested a drug called SEL-212 in 112 adults with chronic gout that didn't improve with standard treatments. Participants received either a low or high dose of SEL-212 or a placebo by IV infusion every 28 days for about 6 months. The main goal was to see if the d…

This study tested a new drug called efanesoctocog alfa in 24 adults with severe hemophilia A. Researchers compared how long it stays in the body versus two existing drugs. Participants received one dose of their usual drug, then later one dose of the new drug, with blood samples …

This completed study reviewed the medical charts of 32 people with Still's disease who developed a serious complication called macrophage activation syndrome (MAS). The goal was to learn more about their symptoms, how long it took for lab values to return to normal, and what trea…