New hemophilia drug may last longer, reducing need for frequent shots

NCT ID NCT06579144

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new drug called efanesoctocog alfa in 24 adults with severe hemophilia A. Researchers compared how long it stays in the body versus two existing drugs. Participants received one dose of their usual drug, then later one dose of the new drug, with blood samples taken over several days. The goal was to see if the new drug lasts longer, which could mean fewer injections for patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

efanesoctocog alfa (a longer-lasting clotting factor)

What this could lead to

If this drug lasts longer in the body, people with hemophilia A may need fewer infusions to prevent bleeding.

What could go wrong

This is a small, early-phase study in 24 people. It only measures drug levels, not actual bleeding prevention. The drug may not work better in real life.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

blood coagulation disease coagulation protein disease hemophilia A severe hemophilia A

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sobi Investigational Site

    Sofia, Bulgaria

  • Sobi Investigational Site

    Bonn, Germany

  • Sobi Investigational Site

    Milan, Italy

  • Sobi Investigational Site

    A Coruña, Spain

  • Sobi Investigational Site

    Valencia, Spain

  • Sobi Investigational Site

    Zaragoza, Spain

  • Sobi Investigational site

    Frankfurt, Germany