Stephanie B. Seminara, Md

This early-stage study tested whether a natural hormone called kisspeptin could help women with hypothalamic amenorrhea (a condition where periods stop due to brain signaling problems) release eggs from their ovaries. Thirteen women received kisspeptin injections under the skin f…

This study tested whether giving pulses of a hormone called kisspeptin could help restart the body's natural hormone production in adults with hypogonadotropic hypogonadism (HH), a condition where the brain doesn't properly signal the reproductive system. Eighteen participants re…

This study aimed to understand how blocking opioid signals in the body affects reproductive hormones in healthy people. Researchers tested 47 adults with different genetic backgrounds, giving some participants an opioid-blocking drug called naloxone while taking frequent blood sa…

This study aimed to understand if blocking natural opioids in the body could affect reproductive hormones in men with a rare condition called hypogonadotropic hypogonadism, which causes low testosterone. Twenty-three men participated, each acting as their own control. Researchers…

This study aimed to understand how people interpret risk information from genetic testing. Researchers tested which visual aids help people most accurately understand their genetic risk percentages. Over 1,000 participants reviewed different risk displays and answered questions a…

This small, early-stage study aimed to understand how a hormone called kisspeptin affects other reproductive hormones in women with Polycystic Ovary Syndrome (PCOS). Eight participants had their hormone levels measured frequently over 36 hours while receiving a kisspeptin infusio…