Stephanie B. Seminara, Md

This study tested a new treatment using kisspeptin for people with hypogonadotropic hypogonadism, a condition where the body doesn't make enough sex hormones. 18 adults received the treatment to see if it could safely boost hormone levels. The goal was to find a better way to man…

This study tested whether a natural hormone called kisspeptin can help women with hypothalamic amenorrhea (a condition where periods stop due to stress, low weight, or over-exercise) release eggs. Thirteen women received daily injections of kisspeptin for two weeks. Researchers u…

This study looked at how a drug that blocks opioids (naloxone) affects hormone signals in the brain related to testosterone. 23 men with a condition called hypogonadotropic hypogonadism (low testosterone) took part. The goal was to understand the body's hormone control, not to tr…

This study looked at how people understand risk from genetic testing. Over 1,000 participants were shown different visual aids and asked to estimate their risk. The goal was to find which visual aid helps people most accurately understand genetic risk and how they feel about shar…

This study looked at how a drug that blocks opioid receptors (naloxone) changes reproductive hormones in healthy adults. Researchers enrolled 47 people who had genetic data available from a biobank. Participants received naloxone infusions, and the team measured changes in hormon…

This small study looked at how a continuous dose of kisspeptin, a brain hormone, changes the body's natural hormone pulses in women with polycystic ovary syndrome (PCOS). Eight women aged 18-45 with PCOS took part. The goal was to learn more about the hormone patterns in PCOS, no…