St. Jude Children's Research Hospital
Clinical trials sponsored by St. Jude Children's Research Hospital, explained in plain language.
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New hope for kids after transplant: study tests safer GVHD prevention
Disease control TerminatedThis study looked at a new way to prevent severe graft-versus-host disease (GVHD) in children who had a bone marrow transplant for blood cancers. The goal was to see if stopping certain immune-suppressing drugs early could lower the risk of severe GVHD. Only 3 children took part …
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 16, 2026 22:49 UTC
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Promising leukemia drug falls short in kids trial
Disease control TerminatedThis study tested a drug called inotuzumab ozogamicin in children with B-cell acute lymphoblastic leukemia (B-ALL) that still had small amounts of cancer cells after standard treatment. The goal was to see if the drug could wipe out those leftover cells. Only 5 children took part…
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 16, 2026 12:48 UTC
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Can a phone app catch childhood eye cancer? study aims to find out.
Diagnosis TerminatedThis study tested a smartphone app called CRADLE that looks for a white glow in the eye (leukocoria), which can be a sign of retinoblastoma, a rare childhood eye cancer. The goal was to see how well the app works compared to a doctor's exam. Only one person took part before the s…
Phase: NA • Sponsor: St. Jude Children's Research Hospital • Aim: Diagnosis
Last updated Jun 16, 2026 22:52 UTC
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Vitamin a and vaccines: a small study that never finished
Knowledge-focused TerminatedThis study looked at whether giving vitamin A supplements to healthy children aged 1 to 4 years old could improve their immune response to the pneumonia vaccine. The researchers planned to compare antibody levels in children who received vitamin A with those who did not. However,…
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:54 UTC
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Scientists dig into Kids' brain tumors to uncover genetic clues
Knowledge-focused TerminatedThis study looked at stored tumor samples from 139 children with brain or spinal cord tumors. Researchers wanted to find DNA changes and markers that could help understand these cancers better. No new treatments were tested; the goal was simply to learn more about the tumors.
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:57 UTC
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Heavy periods and loose joints: a hidden connection?
Knowledge-focused TerminatedThis study looked at women and girls aged 12 to 40 with heavy menstrual bleeding to see if they also have joint hypermobility (loose joints). Researchers wanted to find out if these two issues together might point to an underlying connective tissue disorder. The study was stopped…
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:54 UTC