Can your phone spot eye cancer? app tested for retinoblastoma

NCT ID NCT03016156

Terminated Diagnosis Sponsor: St. Jude Children's Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a smartphone app called CRADLE that uses a photo to detect leukocoria (a white glow in the pupil), which can be a sign of retinoblastoma, cataracts, or glaucoma. Researchers planned to compare the app's accuracy to a standard eye exam in children with these conditions. However, the study was terminated early after enrolling only 1 participant, so no reliable conclusions can be drawn.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Smartphone application (CRADLE)
What this could lead to: If successful, this app could help parents and doctors spot early signs of eye cancer in children using a smartphone, leading to faster diagnosis.
What could go wrong: The study was terminated with only 1 participant, so we have very little data. The app may not be accurate enough to replace standard exams, and results may not apply to all children.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cataract congenital glaucoma glaucoma 3A retinoblastoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CATARACTS INFANTILE GLAUCOMA, CONGENITAL LEUCOCORIA RETINOBLASTOMA

Contacts and locations

Locations

St. Jude Children's Research Hospital

Memphis, Tennessee, 38105-2794, United States

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