Southeast University, China

This study tests whether the steroid dexamethasone, when added to standard care, can lower the chance of death within 90 days for people with a serious lung condition called ARDS caused by sepsis. About 1,474 adults on breathing machines will take part. The goal is to see if this…

This study tests whether a traditional Chinese herbal formula, Xuanbai Shengmai Decoction, can improve survival in adults with acute respiratory distress syndrome (ARDS), a severe lung condition often seen in the ICU. About 308 participants will receive either the herbal decoctio…

This study tests whether a personalized weaning strategy can help adults with chronic heart, brain, or lung conditions leave ventilators earlier. The strategy tailors care based on the main reason a patient struggles to breathe on their own, such as heart or muscle problems. Rese…

This study tests a drug called liposomal amphotericin B in 40 ICU patients who have a severe fungal infection (invasive aspergillosis) and liver problems. The drug is given daily for 2 weeks, followed by 4 weeks of monitoring. The goal is to see if it is safe and effective for th…

This study tests whether an anti-bloating patch can reduce stomach swelling after heart surgery. Stomach bloating is common after cardiac procedures and can slow recovery. The trial will compare standard care alone to standard care plus the patch in 150 adults undergoing elective…

This study looks at whether a special breathing tube procedure (bronchoscopy) can help clear mucus and improve lung function in patients on ventilators who have collapsed lung areas (atelectasis). About 104 adults will be randomly assigned to either standard care or standard care…

This study looks back at medical records from 2,000 adults on breathing machines in the ICU. Researchers want to understand how nutrition-related blood tests change over time and how they relate to patient outcomes like survival and length of hospital stay. The goal is to build a…

This study will use a new 3D imaging device (3D-EIT) to see if it can detect a pattern called 'cyclic on-off switching' of blood flow in the lungs of 40 adults with moderate to severe ARDS who are on mechanical ventilation. The goal is to validate whether this non-invasive, bedsi…

This study will enroll 60 adults with acute hypoxemic respiratory failure (low oxygen levels) to compare three noninvasive breathing supports: CPAP, NIV, and high-flow nasal oxygen. Researchers will use electrical impedance tomography to measure lung strain in real time. The goal…