Shionogi

This study tested a new vaccine called S-268019 to see if it can prevent COVID-19. About 9,900 adults who had never had COVID-19 received either the vaccine or a placebo. Researchers tracked how many people got sick with COVID-19 at least 14 days after their second shot.

This study tested an experimental antiviral drug called S-892216 in 282 adults with mild-to-moderate COVID-19. The goal was to see if the drug could lower the amount of virus in the nose and throat faster than a placebo. Participants had to have symptoms and a positive test for t…

This study tested the safety and how the body processes the antibiotic cefiderocol in 53 hospitalized children aged 3 months to 18 years with serious gram-negative bacterial infections. The goal was to see if the drug is safe and to determine the right dose. The study was complet…

This study looked at how the antibiotic cefiderocol works in hospitalized newborns under 3 months old with serious bacterial infections. Researchers measured how the drug moves through the body and checked for side effects. The goal was to find the right dose for this age group.

This study tested an experimental antiviral pill called S-217622 in over 2,000 adults with mild to moderate COVID-19 who were not hospitalized. Participants started the pill within 3 days of symptoms. The goal was to see if the pill could shorten symptom duration and lower virus …

This study looked at how the drug BPN14770 is handled by the body in people with different levels of liver impairment compared to healthy volunteers. 32 adults took a single dose, and researchers measured drug levels in the blood and checked for side effects. The goal was to unde…

This study looked at how the drug BPN14770 is processed by the body in people with severe kidney impairment compared to healthy volunteers. Fourteen participants took a single dose, and researchers measured drug levels and checked for side effects. The goal was to understand if k…

This study tested a new drug called S-740792 in 99 healthy adults to see if it is safe and how the body handles it. The study also looked at how food and another drug (midazolam) affect S-740792. This is an early-stage trial with no direct treatment benefit for participants.