Shionogi

This study tests a new drug called S-531011, alone or with other cancer treatments, in people with advanced solid tumors that have stopped responding to standard therapies. The goal is to find a safe dose and see if it can shrink tumors or slow cancer growth. About 282 adults wil…

This study tests an experimental antiviral drug called S-337395 in adults with RSV who are at high risk for severe illness but are not hospitalized. The goal is to see if the drug can reduce the amount of virus in the nose and throat faster than a placebo. About 192 participants …

This study tests whether adding an experimental drug called S-606001 to standard enzyme replacement therapy can help adults with late-onset Pompe disease. Pompe disease causes muscle weakness, including breathing muscles. The trial will measure changes in lung function and walkin…

This study tests a drug called naldemedine in children (up to age 18) who are taking or about to take opioids for pain. The drug aims to relieve constipation caused by opioids. Researchers will check how the drug moves through the body and if it is safe. About 24 children will ta…

This early-stage study is testing a new drug called S-892216 in about 40 people with various levels of kidney function, from normal to severe impairment. The main goal is to see how the drug moves through the body and how safe it is. Participants will be grouped by kidney functio…