New hope for kids on painkillers: constipation drug under study

NCT ID NCT05588323

First seen May 02, 2026 · Last updated May 15, 2026 · Updated 3 times

Summary

This study tests a drug called naldemedine in children (up to age 18) who are taking or about to take opioids for pain. The drug aims to relieve constipation caused by opioids. Researchers will check how the drug moves through the body and if it is safe. About 24 children will take part.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OPIOID-INDUCED CONSTIPATION (OIC) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Saint-Pierre Clinical Trials Unit

    COMPLETED

    Brussels, Belgium

  • Chu de Caen

    COMPLETED

    Caen, 14033, France

  • Citta della Salute e della Scienza di Torino

    COMPLETED

    Torino, Italy

  • Hôpital Armand Trousseau Service Hématologie et Oncologie Pédiatrique

    COMPLETED

    Paris, France

  • Hôpital Béclère Service de Pédiatrie Centre de Référence des Maladies Héréditaires du Métabolisme Hépatique (CRMHMH)

    COMPLETED

    Clamart, France

  • Hôpital Jeanne de Flandre Antenne du CIC pédiatrique - Niveau 0 CHU de Lille

    COMPLETED

    Lille, France

  • Instituto Nazionale dei Tumori

    COMPLETED

    Milan, Italy

  • Maternal and Child Health Institute IRCCS Burlo Garofolo, Pain and pediatric palliative care service

    COMPLETED

    Trieste, Italy

  • National Center for Child Health and Development

    NOT_YET_RECRUITING

    Tokyo, Japan

  • PHI University Clinic for Children's , Surgery

    RECRUITING

    Skopje, North Macedonia

  • Universitair Ziekenhuis Brussel (UZBrussel) - Department of Anesthesiology and Perioperative Medicine

    COMPLETED

    Brussels, Belgium

  • University Center Mother Theresa , Hospital - Onco-hematology department

    NOT_YET_RECRUITING

    Tirana, Albania

  • University Clinic for Childrens Diseases , Department of Oncology, Hematology and , Malignant Hemopathy

    RECRUITING

    Skopje, North Macedonia

  • University Clinical Hospital , Mostar

    RECRUITING

    Mostar, Bosnia and Herzegovina

  • University Hospitals Leuven Pediatrisch hemato-oncology

    COMPLETED

    Leuven, Belgium

  • Yeolyan Hematology. , and Oncology Center -

    RECRUITING

    Yerevan, Armenia

Conditions

Explore the condition pages connected to this study.