ALS patients tolerate oral edaravone in Long-Term safety check

NCT ID NCT05568615

First seen Jan 04, 2026 · Last updated May 11, 2026 · Updated 24 times

Summary

This study looked at the safety of an oral form of edaravone for people with ALS, a progressive nerve disease. Fifteen patients who completed earlier studies took the medicine for 10 days every two weeks. Researchers tracked side effects to see if the drug is safe for long-term use.

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Contacts and locations

Locations

  • Fukushima Medical University Hospital

    Fukushima, Fukushima, 960-1295, Japan

  • Kagawa University Hospital

    Kita-gun, Kagawa-ken, 761-0793, Japan

  • Kitasato University Hospital

    Sagamihara-shi, Kanagawa, 252-0375, Japan

  • National Epilepsy Center NHO Shizuoka Institute of Epilepsy and Neurological Disorders

    Shizuoka, 420-8688, Japan

  • National Hospital Organization Chibahigashi National Hospital

    Chiba, Chiba, 260-8712, Japan

  • National Hospital Organization Higashinagoya National Hospital

    Nagoya, Aichi-ken, 465-8620, Japan

  • National Hospital Organization Kumamoto Saishun Medical Center

    Kōshi, Kumamoto, 861-1196, Japan

  • National Hospital Organization Osaka Toneyama Medical Center

    Toyonaka-shi, Osaka, 560-8552, Japan

  • Shiga University of Medical Science Hospital

    Ōtsu, Shiga, 520-2192, Japan

  • Tokyo Metropolitan Neurological Hospital

    Fuchu-shi, Tokyo, 183-0042, Japan

  • Yokohama City University Hospital

    Yokohama, Kanagawa, 236-0004, Japan

Conditions

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