Seattle Children's Hospital
Clinical trials sponsored by Seattle Children's Hospital, explained in plain language.
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Double-Targeting immune cells tested in kids with tough leukemia
Disease control OngoingThis early-stage study is testing a new type of personalized immune cell therapy for children and young adults with a specific type of leukemia that has come back or hasn't responded to other treatments. Doctors take a patient's own immune cells (T-cells), modify them in a lab to…
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New program aims to bridge the gap for families in the hospital
Disease control ENROLLING_BY_INVITATIONThis study is testing a new support program called the Family Bridge Program. It aims to help low-income families from diverse backgrounds better navigate the hospital system and communicate with their child's medical team. A trained guide provides practical help, communication c…
Phase: NA • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Engineered immune cells target Kids' brain tumors in pioneering trial
Disease control OngoingThis early-stage study is testing a new treatment for children and young adults whose brain or spinal cord tumors have come back or haven't responded to standard therapies. Doctors collect the patient's own immune cells, modify them in a lab to recognize and attack cancer cells, …
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Scientists test 'Tag-and-Kill' cancer therapy for tough bone tumors
Disease control OngoingThis early-stage study is testing a new two-part treatment for osteosarcoma that has come back or not responded to standard therapies. Doctors take a patient's own immune cells (T cells), modify them in a lab to recognize a special marker, and then infuse them back. A second drug…
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Brain scans reveal why some kids struggle with weight loss
Disease control OngoingThis study is testing whether adding a weekly medication to family-based behavioral therapy helps children aged 10-12 manage obesity better. Researchers will use brain scans to understand how children's brains respond to food cues and whether this affects weight loss. The goal is…
Phase: PHASE3 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for kids with tough cancers: scientists test 'Re-Trained' immune cells
Disease control OngoingThis early-stage study is testing a new type of personalized cell therapy for children and young adults whose solid tumors have come back or haven't responded to other treatments. Doctors take a patient's own immune cells, modify them in a lab to better recognize and attack cance…
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New hope for kids with tough cancers: Re-Engineered immune cells target leukemia
Disease control OngoingThis study is testing a new cell therapy for children and young adults (up to age 30) whose leukemia or lymphoma has returned or not responded to other treatments. Doctors take a patient's own immune cells (T-cells), modify them in a lab to recognize a protein called CD22 on canc…
Phase: PHASE1, PHASE2 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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New hope for kids with deadly brain tumors: experimental therapy targets cancer directly in the brain
Disease control OngoingThis early-stage study is testing a new type of personalized immune cell therapy called SC-CAR4BRAIN for children and young adults with aggressive brain tumors that have come back or not responded to standard treatments. Doctors collect a patient's own immune cells, modify them i…
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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New hope for kids with tough cancers: genetically engineered immune cells target tumors
Disease control OngoingThis early-phase study is testing the safety and feasibility of a new treatment called CAR T-cell therapy for children and young adults whose solid tumors have come back or not responded to standard treatments. Doctors take a patient's own immune cells, modify them in a lab to be…
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Mar 18, 2026 14:41 UTC
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Can a phone app bridge the language gap in your Doctor's office?
Knowledge-focused OngoingThis study is testing two practical methods to help doctors communicate better with patients who don't speak English well. Researchers are comparing mobile video interpreters (like a video call with a translator) against online training modules for doctors. They're measuring whet…
Phase: NA • Sponsor: Seattle Children's Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC