Double-Barreled CAR-T cells take aim at tough leukemia
NCT ID NCT03330691
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a new type of immunotherapy for children and young adults with leukemia that has come back or not responded to treatment. The therapy uses the patient's own immune cells, modified to recognize two different targets (CD19 and CD22) on leukemia cells, to try to kill them more effectively. The main goals are to see if the treatment is safe and if enough of these special cells can be made for each patient.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Children's and Women's Health Centre of British Columbia
Vancouver, British Columbia, V6H 3V4, Canada
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Riley Hospital for Children
Indianapolis, Indiana, 46202, United States
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Seattle Children's Hospital
Seattle, Washington, 98105, United States