Could a weekly shot help kids with obesity? new trial tests combo therapy
NCT ID NCT04520490
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether adding a weekly injection of exenatide (Bydureon) to family-based behavioral treatment helps children aged 10-12 with obesity lose weight more effectively. The trial involves 63 children and their parents, with weekly sessions over 24 weeks. Researchers will measure changes in body mass index (BMI) and body composition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
exenatide (Bydureon) once weekly injection
What this could lead to
If successful, this combination approach could offer a more effective way to help children with obesity achieve lasting weight control.
What could go wrong
This is a small, early-phase study (63 participants) and results may not apply to all children. The drug exenatide can cause side effects like nausea, and long-term safety in children is not yet established.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Seattle Children's Hospital
Seattle, Washington, 98105, United States