Rush University Medical Center

This study tests whether adding a patient's own bone marrow stem cells to standard ACL surgery helps the new ligament heal and integrate better. One hundred adults with a recent ACL tear will receive either standard surgery or surgery plus stem cells. The main outcome is MRI-meas…

This study looks at whether taking a common ulcerative colitis medication (5-ASA) in the morning versus the evening can better control hidden inflammation and improve gut health. About 32 adults with inactive ulcerative colitis but signs of low-level inflammation will take their …

This study compares two methods to prevent infections during first-time penile implant surgery for erectile dysfunction. One group receives the standard antibiotic rinse, the other uses Irrisept, a simpler cleaning solution. Researchers will follow 200 men for one year after surg…

This study tests whether injecting a patient's own blood into the chest can stop air leaks after lung cancer surgery. About 60 adults who have an air leak three days after surgery will receive the blood patch. The goal is to see if it prevents prolonged leaks, shortens hospital s…

This study tests whether an injection of a patient's own bone marrow concentrate, given right after meniscus surgery, can prevent or slow the development of arthritis in the knee. One hundred adults with a torn meniscus will be randomly assigned to receive either the bone marrow …

This study tests whether giving menstrual cups to 408 economically vulnerable women in Kenya can reduce bacterial vaginosis (BV) and sexually transmitted infections (STIs). Participants use the cups during their periods and are followed for up to 3 years. The goal is to see if th…

This study tested a new way to give radiation for prostate cancer using advanced MRI scans to guide the treatment. 54 men with localized prostate cancer received either 5 sessions of radiation to the whole prostate or a longer course with a targeted boost to visible tumors. The g…

This study tests a program called Black Girls Move, designed to help Black teenage girls (9th and 10th grade) and their mothers become more active and eat healthier. The goal is to prevent obesity and related health problems like diabetes. About 120 daughter-mother pairs will tak…

This study tests whether the MIND diet, a mix of the Mediterranean and DASH diets, can slow down memory loss and prevent dementia in people who have had a stroke. Researchers will follow 250 stroke survivors aged 55 and older for 2 to 3 years, comparing those who follow the MIND …

This study compares a one-week virtual talk therapy (Cognitive Processing Therapy) to a five-day relaxation training for reducing PTSD symptoms. About 140 adults with PTSD will participate to see which approach works better and how. The goal is to find faster, more effective ways…

This study tests whether taking probiotics can reduce symptoms and improve quality of life for people with Long COVID. Researchers will track changes in symptom severity and overall well-being in 180 adults. The goal is to find a simple, safe way to help those still struggling af…

This study tests whether trained peer mentors—people who have cared for a loved one with Lewy body dementia—can help current caregivers feel less stressed and more knowledgeable. About 500 caregivers across the U.S. will be randomly assigned to receive either weekly mentor coachi…

This study looks at whether encouraging people from underserved communities to take part in rewarding community activities—like social groups or recreational events—can help reduce depression symptoms, increase physical activity, and support weight loss. About 102 adults with mil…

This study follows 22 adults who have spine surgery (LLIF or ALIF) to see how long hip and leg weakness lasts. Participants will have their hip and knee strength measured before surgery and again at 6 weeks, 12 weeks, and 6 months after. The goal is to learn the exact timing of w…

This study looks at ways to get patients to complete follow-up surveys after shoulder surgery. About 400 adults having shoulder arthroscopy will either receive education about the importance of surveys or get Amazon gift cards for completing them. The goal is to see which method …

This study looks at whether a newer type of hip implant (modular dual mobility) leads to higher levels of metals like cobalt and chromium in the blood compared to a standard implant. About 52 adults getting a first-time hip replacement will be randomly assigned to one of the two …

This study looks at how Western habits—like drinking alcohol and eating late—might raise the risk of colorectal cancer. Twelve adults who have had colon polyps in the past will try four different weekly routines, including eating at normal times or late, with or without alcohol. …

This study aims to find out if extra digestive juices from the new pancreas cause weight gain after a pancreas transplant. Researchers will measure a digestive enzyme in the stool of 50 transplant recipients and see if it relates to how much weight they gain. The goal is to bette…

This study looks at whether people can drive safely right after minor surgery with newer, short-acting anesthesia drugs. About 625 adults who have minor procedures (like hand or foot surgery) will take a driving simulator test before leaving the clinic. The goal is to see if cert…