Queen Mary University Of London

This study investigates whether a patient's own platelet concentrate, called A-PRF, can improve early wound healing after tooth extraction in people at high risk for medication-related osteonecrosis of the jaw (MRONJ). Participants are adults who have taken or are taking bone-str…

This study looks at whether a long-acting injectable HIV prevention drug (cabotegravir) can be delivered fairly and effectively in NHS sexual health clinics. Researchers will follow 200 people taking the drug for 12 months, along with 20 healthcare professionals, to see how well …

This pilot study looks at people with a blood clot in the heart (left ventricular thrombus) who have been on blood thinners for at least 3 months. Half will stop their medication and half will continue, to see which approach is safer. The goal is to find the best treatment durati…

This study will compare aspirin tablets to daily injections of low molecular weight heparin (LMWH) for preventing dangerous blood clots in people who break their hip. Over 21,000 patients aged 60 and older across 96 UK hospitals will take part. Hospitals will switch between the t…

This trial tests a software device called AI-TRiPS that uses real-time data from ambulances to predict the risk of death, bleeding, kidney injury, and need for blood transfusion in trauma patients. The tool displays these predictions to hospital trauma teams before the patient ar…

This study aims to learn more about how tendons work and why they get sick. Researchers will collect small pieces of tendon tissue that are normally thrown away during planned surgeries in adults. Participants do not need to do anything extra—just give permission to use the lefto…

This study looks at whether adding bone graft up to a person's natural bone line (IPD) or slightly beyond it leads to better long-term stability after dental implant surgery. Twenty-eight adults needing a tooth replacement in the upper jaw will receive an implant and bone graft, …