New support program aims to help young people stop laughing gas misuse
NCT ID NCT07716293
First seen Jul 21, 2026 · Last updated Jul 22, 2026 · Updated 1 time
Summary
This study tests a new brief support program for people who have nerve damage from using nitrous oxide (laughing gas). The program provides information and practical strategies to help manage emotions, cope with stress, and reduce use. Ten participants at a London hospital will receive the program alongside their usual care and give feedback to help improve it for a larger future study.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a brief manualised psychosocial intervention comprising information provision, psychoeducation, goal setting, coping strategies, self-management strategies, and Cognitive Behavioural Therapy techniques (including mindfulness and cognitive reframing), delivered over up to four weekly sessions
- What this could lead to
- If successful, this program could offer a practical way to help young people reduce nitrous oxide use and improve their mental health and quality of life.
- What could go wrong
- This is a very small early-stage study with only 10 participants, so results may not apply to everyone. The program may not be effective or engaging for all users.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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16 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed clinical neurological diagnosis related to N₂O use. * Experiencing mild to moderate psychological distress. * Aged 16-65 years. * Able to communicate in English. * Able and willing to give informed consent. Exclusion Criteria: * Other causes of neurological symptoms. * Currently receiving another structured psychosocial intervention. * Severe psychiatric distress.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Queen Mary University of London
London, E1 4NS, United Kingdom