Prisma Health-upstate
Clinical trials sponsored by Prisma Health-upstate, explained in plain language.
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Peer coaches boost opioid treatment in rural areas
Disease control CompletedThis study looked at whether having a peer support specialist (a person with lived experience) can help people with opioid use disorder begin and continue taking buprenorphine, a medication that reduces cravings. Ninety adults from rural South Carolina joined the study and were c…
Phase: NA • Sponsor: Prisma Health-Upstate • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New imaging reveals how CS1 drug may reshape lungs in rare Heart-Lung disease
Disease control CompletedThis study tested whether a drug called CS1 can improve the structure of small lung arteries in people with pulmonary arterial hypertension (PAH), a serious disease that makes it hard to breathe. Seven adults already taking CS1 in an expanded access program had special CT scans a…
Sponsor: Prisma Health-Upstate • Aim: Disease control
Last updated May 11, 2026 20:51 UTC
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Can computer therapy and coaching boost opioid recovery?
Disease control CompletedThis study looked at whether adding computer-based cognitive behavioral therapy (CBT4CBT) and peer recovery coaching to standard buprenorphine treatment helps adults with opioid use disorder reduce drug use. 92 adults taking buprenorphine were randomly assigned to receive standar…
Phase: NA • Sponsor: Prisma Health-Upstate • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Friendly help eases depression in opioid recovery
Symptom relief CompletedThis study tested whether peer support workers could help people with opioid use disorder feel less depressed and anxious. 40 adults receiving medication for opioid use disorder took part. They met with a peer specialist for weekly problem-solving sessions over 12 weeks. The goal…
Phase: NA • Sponsor: Prisma Health-Upstate • Aim: Symptom relief
Last updated May 17, 2026 04:41 UTC
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Virtual reality brings peace to hospice patients and families
Symptom relief CompletedThis study tested whether a shared virtual reality (VR) nature experience could help hospice patients and their caregivers feel better. 26 patient-caregiver pairs tried a synchronized VR program with calming nature scenes. Researchers measured quality of life, fear of death, pain…
Phase: NA • Sponsor: Prisma Health-Upstate • Aim: Symptom relief
Last updated May 17, 2026 04:34 UTC
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Pandemic pregnancy puzzle: scientists probe placenta for COVID clues
Knowledge-focused CompletedThis study looked at placentas and umbilical cord blood from 68 women who had COVID-19 during pregnancy. Researchers checked for changes in the placenta's structure, genes, and signs of inflammation. The goal was to learn how the infection might affect the baby, not to test a tre…
Sponsor: Prisma Health-Upstate • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC