Prisma Health-upstate
Clinical trials sponsored by Prisma Health-upstate, explained in plain language.
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Immunotherapy combo studied for rare tumors, but trial stopped early
Disease control TerminatedThis study tested a combination of two immunotherapy drugs (durvalumab and tremelimumab) in people with advanced rare solid tumors that had not responded to standard treatments. The goal was to see if the drugs could shrink tumors and to check for side effects. The trial was term…
Phase: PHASE2 • Sponsor: Prisma Health-Upstate • Aim: Disease control
Last updated May 17, 2026 07:05 UTC
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Hand fracture study compares two fixation techniques
Disease control TerminatedThis study compared two ways to surgically fix unstable hand fractures: using a buried wire inside the bone versus a plate and screws on the outside. It included 25 adults with broken hand bones that needed surgery. The study was stopped early, so results are limited.
Phase: NA • Sponsor: Prisma Health-Upstate • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Promising cancer drug trial halted early despite genetic target
Disease control TerminatedThis study tested a drug called tazemetostat in people with advanced solid tumors that have a specific genetic change (ARID1A mutation). The drug works by blocking a protein (EZH2) that helps these tumors grow. The trial aimed to see if the drug could shrink tumors or stop them f…
Phase: PHASE2 • Sponsor: Prisma Health-Upstate • Aim: Disease control
Last updated May 11, 2026 20:41 UTC