Paul Szabolcs

This study tests if high-dose chemotherapy followed by a stem cell transplant can help control severe Crohn's disease in children and adults aged 10 to 60. The treatment aims to reset the immune system and reduce inflammation. Researchers will monitor side effects and how long sy…

This study is testing a less intense chemotherapy and radiation regimen before a stem cell transplant for children and young adults up to age 55 with non-cancerous blood disorders like immune deficiencies, anemias, and metabolic diseases. The goal is to see if this gentler prepar…

This study tests if a lung transplant followed by a bone marrow transplant can help people with both severe lung disease (like pulmonary fibrosis or COPD) and bone marrow failure. Up to 8 adults aged 18-60 will receive a lung transplant first to improve breathing, then a bone mar…

This study tests a stem cell transplant for people with common variable immunodeficiency (CVID) and other immune disorders. The goal is to replace the faulty immune system with a healthy donor's stem cells. Participants are aged 5 to 40 and will receive a reduced-intensity transp…

This study tests a stem cell transplant for people aged 8-24 with severe systemic sclerosis (scleroderma) that hasn't improved with standard treatments. The approach uses high-dose therapy to reset the immune system, followed by a transplant of the patient's own blood stem cells.…

This study tracks children and adults with non-cancerous blood or immune disorders who receive a stem cell transplant using a milder chemotherapy regimen. The goal is to see how well the transplant works and to monitor side effects like graft-versus-host disease. Up to 50 partici…