Nrg Oncology
Clinical trials sponsored by Nrg Oncology, explained in plain language.
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Prostate cancer combo: does adding chemo after surgery keep cancer away?
Disease control CompletedThis study looked at 612 men with prostate cancer that had been removed by surgery. It compared standard treatment (hormone therapy plus radiation) against the same treatment plus the chemotherapy drug docetaxel. The goal was to see if adding chemo helps keep the cancer from comi…
Phase: PHASE2, PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Could a diabetes drug boost lung cancer treatment?
Disease control CompletedThis study looked at whether adding metformin (a common diabetes medicine) to standard chemotherapy and radiation helps people with stage III non-small cell lung cancer live longer without their cancer getting worse. About 170 adults with advanced lung cancer took part. The goal …
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Can less radiation beat throat cancer without chemo?
Disease control CompletedThis study tested whether a lower dose of radiation therapy, with or without the chemotherapy drug cisplatin, can effectively treat advanced oropharyngeal (throat) cancer in patients who are non-smokers. The trial enrolled 316 people with p16-positive cancer, a type linked to HPV…
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New radiation technique aims to protect memory in lung cancer patients
Disease control CompletedThis study tested whether avoiding the hippocampus during whole-brain radiation could reduce memory side effects in people with small cell lung cancer. Over 400 patients received either standard whole-brain radiation or a version that spares the hippocampus. The goal was to see i…
Phase: PHASE2, PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Zapping tumors with precision radiation may help control limited metastatic breast cancer
Disease control CompletedThis study looked at whether adding focused radiation (SBRT) or surgery to standard treatments like chemo or hormone therapy helps people with breast cancer that has spread to just one or two places. 129 participants were randomly assigned to get standard care alone or standard c…
Phase: PHASE2, PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Shorter radiation after prostate surgery may be just as good
Disease control CompletedThis study tested whether a shorter course of higher-dose radiation (hypofractionated) works as well as standard radiation after prostate removal in 296 men with prostate cancer. The main focus was on quality of life, especially urinary and bowel function. The goal is to find a t…
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New drug combo aims to stop high-risk prostate cancer in its tracks
Disease control CompletedThis study tested whether adding the drug niraparib to standard radiation and hormone therapy can help prevent high-risk prostate cancer from coming back. Niraparib blocks a protein that cancer cells use to repair their DNA, which may kill them. The trial enrolled 22 men with agg…
Phase: PHASE1, PHASE2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Cancer Survivors' sex drive gets a boost: bupropion shows promise
Symptom relief CompletedThis study tested whether bupropion, a medication that affects brain chemicals, can improve low sexual desire in women who have had breast or gynecologic cancer. About 230 women took either bupropion or a placebo pill for 9 weeks. The main goal was to see if their self-reported s…
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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New radiation approach targets multiple tumors at once in early trial
Knowledge-focused CompletedThis early-phase trial tested a precise, high-dose radiation technique called stereotactic body radiotherapy (SBRT) in 42 patients with breast, lung, or prostate cancer that had spread to several places in the body. The main goal was to find the safest dose and check for side eff…
Phase: PHASE1 • Sponsor: NRG Oncology • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Can extra care planning keep prostate cancer Survivors' hearts healthy?
Knowledge-focused CompletedThis study looked at whether giving prostate cancer survivors more detailed survivorship care plans helps them get better follow-up care for heart health. The study involved 550 men who had radiation and hormone therapy, which can increase risks for diabetes and heart problems. R…
Phase: NA • Sponsor: NRG Oncology • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC