Nrg Oncology
Clinical trials sponsored by Nrg Oncology, explained in plain language.
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Could extra chemotherapy after prostate surgery keep cancer away longer?
Disease control CompletedThis study looked at men with prostate cancer who had their prostate removed. It compared standard treatment (hormone therapy plus radiation) against the same treatment plus chemotherapy (docetaxel). The goal was to see if adding chemo helps prevent the cancer from coming back or…
Phase: PHASE2, PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 17, 2026 05:48 UTC
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Could a diabetes drug boost lung cancer treatment?
Disease control CompletedThis study looked at whether adding metformin (a common diabetes medicine) to standard chemotherapy and radiation therapy helps people with stage III non-small cell lung cancer live longer without the cancer growing. About 170 people took part. The goal was to see if the combinat…
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 17, 2026 05:46 UTC
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Can zapping or cutting out a few cancer spots boost survival in metastatic breast cancer?
Disease control CompletedThis study looked at whether adding focused radiation (SBRT) or surgery to usual treatments (like chemo or hormone therapy) helps people with breast cancer that has spread to just 1-2 places in the body. 129 participants were randomly assigned to get standard care alone or standa…
Phase: PHASE2, PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New drug combo shows promise in keeping High-Risk prostate cancer at bay
Disease control CompletedThis study looked at whether adding a drug called niraparib to the usual treatment (radiation plus hormone therapy) can help prevent high-risk prostate cancer from growing or coming back. Niraparib works by blocking a repair process that cancer cells rely on, causing them to die.…
Phase: PHASE1, PHASE2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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Shorter radiation course may be just as effective after prostate surgery
Disease control CompletedThis study tested whether a shorter, more intense radiation schedule (hypofractionated) works as well as the standard longer schedule after prostate cancer surgery. About 296 men who had their prostate removed took part. The goal was to see if the shorter treatment could control …
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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Could less radiation be enough for certain throat cancers?
Disease control CompletedThis study looked at whether a lower dose of radiation therapy, with or without the chemotherapy drug cisplatin, is safe and effective for people with advanced oropharyngeal (throat) cancer that is linked to HPV (p16 positive) and occurs in non-smokers. About 316 participants wer…
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Can a depression drug rekindle desire in cancer survivors?
Symptom relief CompletedThis study tested whether bupropion, a medication often used for depression, can improve low sexual desire in women who have had breast or gynecologic cancer. About 230 women took either bupropion or a placebo pill for 9 weeks. The goal was to see if the drug could safely boost d…
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated May 17, 2026 05:46 UTC
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Can brain radiation be smarter? new study tests Memory-Sparing approach
Symptom relief CompletedThis study looked at two types of brain radiation for people with small cell lung cancer that had spread. One method treated the whole brain, while the other tried to avoid the memory center (hippocampus) to reduce thinking and memory side effects. The trial enrolled 418 patients…
Phase: PHASE2, PHASE3 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated May 11, 2026 20:53 UTC
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New radiation approach aims to tame multiple tumors at once
Symptom relief CompletedThis early-stage study tested a precise, high-dose radiation technique called SBRT in 42 adults with breast, lung, or prostate cancer that had spread to several places in the body. The main goal was to find the safest dose and check for side effects. Researchers hope this approac…
Phase: PHASE1 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated May 11, 2026 20:47 UTC
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Can extra care planning keep prostate cancer Survivors' hearts healthy?
Knowledge-focused CompletedThis study looked at whether giving prostate cancer survivors more detailed survivorship care plans helps them get better follow-up care for heart health. The study involved 550 men who had radiation and hormone therapy, which can raise the risk of diabetes and heart problems. Re…
Phase: NA • Sponsor: NRG Oncology • Aim: Knowledge-focused
Last updated May 14, 2026 12:05 UTC