Northwestern University

This study tests whether lisinopril, a widely used blood pressure medication, can slow the progression of non-alcoholic fatty liver disease (NAFLD) and lower the risk of liver cancer. About 45 adults with advanced liver scarring (fibrosis) will take lisinopril for a period, and r…

This study tests a combination of two drugs, nintedanib and azacitidine, in older adults with a type of acute myeloid leukemia (AML) that has certain genetic features. Participants are not candidates for or have declined standard intensive chemotherapy. The goal is to find the sa…

This study compares a new, remotely delivered weight-loss program (EVO) to the standard Diabetes Prevention Program (DPP) in adults with obesity (BMI 30-45). Researchers want to see which program helps people lose more weight over 6 months and which is more cost-effective. Partic…

This study tests whether adding two drugs—pembrolizumab and tazemetostat—after standard stem cell transplant or CAR-T cell therapy can help prevent aggressive B-cell lymphoma from coming back. About 32 adults who have already had or are about to have one of these treatments will …

This early-phase study tests an experimental drug called tomivosertib in 15 adults whose acute myeloid leukemia (AML) has returned or not responded to prior treatments. The main goal is to find the safest dose that also shows signs of fighting the cancer. Participants take the dr…

This study tests whether atorvastatin, a widely used cholesterol-lowering drug, can reduce the risk of colon cancer in people with long-standing ulcerative colitis who carry a specific gene mutation (P53). About 42 participants will receive either atorvastatin or a placebo for a …

This early-phase study tests a low-dose oral minoxidil pill to help people with permanent hair loss caused by chemotherapy. Fourteen adults who finished chemo at least six months ago will take the pill and have their hair regrowth checked every 12 weeks. The goal is to see if thi…

This study tests a special arm exercise therapy for people who recently had a stroke and have trouble reaching outward. About 86 participants will receive either the new therapy or standard care during rehab and be followed for a year. The goal is to see if the therapy reduces ar…

This early study tests a chemical-free microbubble bath system in 20 people aged 2 and older with skin diseases like epidermolysis bullosa, ichthyosis, atopic dermatitis, or psoriasis. The therapy aims to clean wounds, reduce odor and itch, and improve skin healing. Researchers w…

This study tests whether a "Patient Navigation 2.0 Checklist" helps Chinese adults in Chicago get recommended cancer screenings and address social needs like housing or food. Researchers will track 600 participants to see if the checklist improves care and resolves barriers. The …

This study tests whether showing a short video about anesthesia before a scheduled C-section helps patients understand their options and make more informed decisions. About 70 English-speaking adults will watch the video at least 24 hours before their procedure. Researchers will …

This study looks at skin and blood samples from 505 children with eczema (atopic dermatitis) to find biological markers that explain the disease. Researchers want to see if children's eczema is similar to adult eczema and if blood tests can predict skin problems. The goal is to b…

This study looks at how electrical brain stimulation affects brain cells and language areas during surgery for epilepsy or brain tumors. Researchers will monitor 65 patients as they do simple tasks like reading or naming pictures. The goal is to better understand how stimulation …

This study aims to learn if hearing aid settings tailored to a person's listening strategy help them understand speech better than standard settings. About 30 adults with sensorineural hearing loss will wear hearing aids and listen to sentences in noise. They will repeat what the…