New combo aims to prevent lymphoma relapse after transplant or CAR-T

NCT ID NCT06242834

First seen Nov 01, 2025 · Last updated May 08, 2026 · Updated 24 times

Summary

This study tests whether adding two drugs—pembrolizumab and tazemetostat—after standard stem cell transplant or CAR-T cell therapy can help prevent aggressive B-cell lymphoma from coming back. About 32 adults who have already had or are about to have one of these treatments will receive the drug combination. The goal is to see if this approach improves the chance of staying cancer-free longer than current standard care.

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Contacts and locations

Locations

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.