New York State Psychiatric Institute

This study tests a new mindfulness program called MINDS-UP to help prevent substance use in children and teens aged 10 to 14. Researchers will compare kids who do a sports-based prevention program alone to those who also learn mindfulness. The goal is to see if the program is pra…

This study compares two types of job support for adults with obsessive-compulsive disorder (OCD) who are unemployed but want to work. All 40 participants will receive up to 12 sessions of a proven OCD therapy called exposure and response prevention. Half will also get a specializ…

This study looks at whether two sleep treatments—talk therapy for insomnia and a device that enhances deep sleep—can improve thinking skills and daily function in older adults with mild memory problems and poor sleep. Fifty participants aged 60-85 will be randomly assigned to one…

This study looks at how stress and suicidal thoughts are linked in people with major depressive disorder, and how ketamine might help by affecting stress-related brain pathways. Researchers will use smartphone tracking and PET brain scans to monitor 12 participants. The goal is t…

This study looks at how the drug Cobenfy changes dopamine activity in the brains of people with schizophrenia. Twelve participants will take Cobenfy for 5 weeks and get PET and MRI scans before and after treatment. The goal is to understand how the drug works, not to test if it i…