New York State Psychiatric Institute

This study tested a web-based addiction treatment program that was culturally adapted for American Indians and Alaska Natives. 53 adults in outpatient treatment used the program for 12 weeks. The goal was to see if it helped them stay away from drugs and alcohol and to decide if …

This study tested whether a common antiviral drug, valacyclovir, could slow memory decline in people with mild cognitive impairment (MCI) who also carry antibodies for herpes simplex virus. Fifty adults aged 50-95 took either the drug or a placebo for 52 weeks. The goal was to se…

This study tested whether blocking a nerve cluster called the SPG can reduce withdrawal symptoms in people with opioid use disorder. Only 3 people took part, and the goal was to see if the approach is safe and worth studying further. It did not provide addiction treatment or medi…

This study tested whether interpersonal psychotherapy (IPT) works as well as proven therapies like prolonged exposure and relaxation for people with chronic post-traumatic stress disorder (PTSD). Researchers enrolled 110 adults with at least moderately severe PTSD. The goal was t…

This study tested whether ketamine, a drug that blocks certain brain signals, can help people with tinnitus (ringing in the ears). 42 adults with chronic tinnitus received both ketamine and a placebo on different days. Researchers used brain scans to measure changes in brain chem…

This study tested whether a mobile app (mSBIRT) helps community health workers in Mozambique better identify and assist people who drink too much. Over 500 health workers took part, comparing the app to standard training. The goal was to see which approach is more effective and a…

This study looked at why Interpersonal Psychotherapy (IPT) helps people with PTSD. Unlike most PTSD therapies, IPT does not involve re-living traumatic memories. Instead, it focuses on improving relationships and emotional awareness. Researchers measured emotional awareness in 29…

This study tested two methods to encourage COVID-19 testing among people who use opioids: having friends refer others (chain referral) and using trusted community members (credible messengers). About 500 people took part. The goal was to see which method got more people tested an…

This study looked at how to make mental health care more available in Sub-Saharan Africa. Researchers worked with 901 clinic staff in Mozambique to train local health workers and use existing community programs. The goal was to find cost-effective ways to help more people get the…